2007-08-22

Misguided fluoride

Even though the Athens community is progressive, the Athens-Clarke County government is apparently following decayed wisdom on preventing tooth decay by engaging in the forced medication of the population through our water supply with the addition of a fluoride compound. According to readings available through the Fluoride Action Network website and similar websites, ingestion of fluoride is linked to numerous health problems including bone cancer, fragile bones, decreased intelligence, kidney and liver damage, and lowered fertility.

When you consider what is generally known about fluoride and how it is used to actually prevent tooth decay, these claims are quite credible. For instance, fluoride rinses contain sodium fluoride for which users are instructed to swish for a minute and not to swallow. The instructions further say to call poison control if more than one dose is accidentally swallowed. What quantity of fluoride compounds do we swallow over time through Athens' drinking water? We actually cannot control the amount we are exposed because different people drink different amounts of tap water. Fluoride helps teeth by topical application, not ingestion. One part per million of fluoride, the standard employed by Athens, is insignificant to help teeth through exposure, but ingesting fluoride can lead to fluorosis of teeth and delayed eruption of teeth in children.

The readings also claim that studies show that last century's improvement in dental health came through public education and in many cases actually preceded fluoridation of public water. There are studies that show no correlation between a community's dental health and its ingestion of fluoride compounds.

The real effort against water fluoridation should be at the federal level where the Environmental Protection Agency could ban the addition of fluoride compounds to public water. However, I cannot believe that an educated community like Athens is following the outdated ideas of the early 20th century that are now shown to be dangerous.

10 comments:

Winfield J. Abbe said...

The late John Yiamouyiannis, Ph.D. and the late Dean Burk, Ph.D. are two of the pioneers in this subject. Dean Burk (1904-1988) earned a Ph.D. at an early age of 23 at UC Berkeley. A beautiful statement of his life is published in Fluoride 22, 3 (1989) by Professor H. L. McKinney of the University of Kansas. After winning prizes for cancer research and co authoring a paper which was one of the most cited papers in chemistry, Dr. Burk, who has also been described as one of the world's greatest biochemists, having worked with another of the greatest biochemists, Otto Warburg, M.D., Ph.D. in Germany, he spent the last part of his life with the water flouridation issue, which was first brought to his attention by the other distinguished and courageous researcher in this field Dr. Yiamouyiannis. It is difficult to find polite words to describe the ignorant so and so's running the Athens Clarke County government, who choose to disregard the overwhelming evidence against flouridation of public water supplies, largely initiated by these to scientists. This is a very good and enlightening post by Adrian. By the way, Samuel S. Epstein, M.D., whose letter to the Harvard Crimson, is the same scientist the former provost Karen Holbrook would not invite to the University of Georgia to dispute the false and misleading statements on cancer by the CEO of the American Cancer Society as documented in "University Fails to Offer Another Viewpoint" by Winfield J. Abbe, Ph.D., published at the site of Ann Fonfa, also a signer of the petition www.annieappleseedproject.org. I donated the book: "The Politics of Cancer Revisited" by Samuel S. Epstein, M.D., East Ridge Press, 1998 to the UGA Library as they did not have a copy there at the time a few years ago.

66 said...

If Winfield J. Abbe is opposed to fluoridation, I have no choice but to support fluoridation. (He wanted a FERRIS WHEEL at the Southeast Clarke Park instead of the skatepark!)

nyscof said...

Study Proves Fluoridation is Money Down the Drain

New York - October 2009 -- Children’s cavity rates are similar whether water is fluoridated or not, according to data published in the July 2009 Journal of the American Dental Association by dentist J.V. Kumar of the NY State Health Department (1).

In 2008, New York City spent approximately $24 million on water fluoridation ($5 million on fluoride chemicals)(1a). In 2010, NYC’s fluoride chemicals will cost $9 million (1b).

Fluoride in water at “optimal” levels (0.7 – 1.2 mg/L) is supposed to reduce tooth decay without creating excessive fluorosis (fluoride-discolored and/or damaged teeth). Yet cavities are rampant in NY’s fluoridated populations (1c).

Attempting to prove that fluorosed teeth have fewer cavities, Kumar uses 1986-1987 National Institute of Dental Research (NIDR) data which, upon analysis, shows that 7- to 17-year-olds have similar cavity rates in their permanent teeth whether their water supply is fluoridated or not (Table 1).

In 1990, using the same NIDR data, Dr. John Yiamouyiannis published equally surprising results in a peer-reviewed journal. He concluded, “No statistically significant differences were found in the decay rates of permanent teeth or the percentages of decay-free children in the F [fluoridated], NF [non-fluoridated], and PF [partially fluoridated] areas.” (2).

Kumar divided children into four groups based on their community’s water fluoride levels:

Less than 0.3 mg/L where 55.5% had cavities

From 0.3 to 0.7 mg/L where 54.6% had cavities

Optimal 0.7 to 1.2 mg/L where 54.4% had cavities

Over 1.2 mg/L where 56.4% had cavities

Continued:

http://tinyurl.com/MoneyDownTheDrain

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Winfield J. Abbe said...

Fluoride Vol. 34 No. 2 159-160 2001 Tribute 159
TRIBUTE TO JOHN YIAMOUYIANNIS
Translation from the Japanese Journal of Fluoride Research, No. 19, Nov. 2000, p. 1
Dr John Yiamouyiannis, biochemist and founder of the Safe Water Foundation,
USA, died October 8, 2000, passing away peacefully in sleep at his
home in Delaware, Ohio, surrounded by members of his family.
Since 1990, when he first came to Japan to deliver a special lecture at our
invitation, a deep bond of respect and understanding developed between us
in sharing a common goal to end water fluoridation. Here I wish to extend
my heartfelt condolences to his family.
Dr Yiamouyiannis received his undergraduate degree from the University
of Chicago and afterward, in 1967, earned his PhD in biochemistry at the
University of Rhode Island. Upon completing a year of postdoctoral research
at Western Reserve Medical School, he became a biochemical editor
at Chemical Abstracts Service, the world’s largest center for chemical information,
in Columbus, Ohio. There, while reviewing numerous biochemical
reports on fluoride, he became aware of many of the health-damaging
effects of fluoride. His subsequent activity opposing water fluoridation
based on this knowledge prompted efforts by the National Institute of Dental
Research to have CAS silence him or risk losing substantial US Public
Health Service funding. This action ultimately compelled him to resign from
his position at CAS.
In this setback to his career, his was not the first in the controversy over
fluoridation. Even such accomplished physicians as Drs Ionel F Rapaport
and George L Waldbott were severely oppressed in the early stages of the
dispute over fluoridation. Even today, similar reprisals continue, as can be
seen in the case of Forsyth Dental Research Center toxicologist Phyllis J
Mullenix, PhD, and USEPA cancer scientist William Marcus, PhD. These
actions are described by Professor Paul Connett in his “Fluoride: A Statement
of Concern”, which is translated into Japanese in this issue of the Journal
of the Japanese Society for Fluoride Research, as “a sickening thread
that runs throughout this sorrowful 50-year history of fluoride promotion by
agencies of the US Public Health Service.”
Dr Y, however, did not bow to pressure or let himself become a victim.
Instead, he chose the path of maximum resistance to oppose corrupt authority,
not to flatter it. What he had to endure is vividly described in his wellknown
book, Fluoride the Aging Factor. His indomitable courage made him
a hero to many who were like-minded. But organizations like the American
and British dental associations and even government agencies like the US
Public Health Service and the Centers for Disease Control and Prevention
tried to avoid confrontation with him, admitting that “Dr Yiamouyiannis is
160 Murakami
conversant with the literature” and “running up against Dr Yiamouyiannis is
not recommended.”
Dr Y’s studies with Dr Dean Burk to determine whether cancer death rates
increased after fluoridation in the 1950s caused great concern among many
Americans and prompted Congressional hearings in 1977 followed by a 21-
day court trial in Pennsylvania. There the presiding judge was compellingly
convinced of the adverse effects of fluoridation and ordered its halt as a
public health hazard. His decision, however, was overruled on jurisdictional
grounds, and at an administrative level fluoridation policy remained unchanged.
Twenty-three years later, in June 2000, Congressional hearings were again
held. This time USEPA scientist Dr J William Hirzy testified, urging federal
lawmakers to recognize that fluoridation causes great harm and should be
suspended. How regrettable that Dr Yiamouyiannis is not alive to see this
happen.

Continued below:

Winfield J. Abbe said...

Continued from above:
Dr Yiamouyiannis, you were a great leader, and the work you did was a
great achievement. The alarm you sounded was heard by many people
around the world. I pray for the repose of your soul, and I trust your spirit
has flown to the heavens, from whence the wisdom of your Greek ancestors
might be heard today to correct such an outrageous mistake as fluoridating
our drinking water.
Tohru Murakami, DDS, PhD
Editor, Japanese Journal of Fluoride Research
1-5-16 Kamikoide-machi
Maebashi-shi
Gunma-ken, 371 0037, Japan
CORRECTION
Endemic fluorosis in Southern Rajasthan, India by SL Choubisa. Fluoride
2001;34(1):61-70.
In Table 2 (page 65) the first entry of the last column should read
59/558. The author's name in the headers on pages 66 and 68 should
be Choubisa. In the first line of the Acknowledgements (page 69) Environments
should read Environment.
Below it states: "This blog does not allow anonymous comments" It is unfortunate that anonymous cowards are permitted to make false and misleading and meaningless statements about me as one has above.
Winfield J. Abbe, Ph.D., Physics
150 Raintree Ct.
Athens, GA 30607
wjabbe@aol.com
As a post script to the above quotation, everyone should observe the deafening silence from the "professors" at UGA in chemistry and biochemistry, who are the "experts" in this subject.
Could it be that they are silent because they might lose some funding or favor from the government which provides them their research funding should they express an opinion, signed with their true names, addresses and telephone numbers, against the true dangers of fluoridation of the public water supplies as expressed by the detailed scientific studies by the genius Dean Burk, Ph.D. and his associate John Yiamouyiannis, Ph.D. and numerous other subsequent studies? This is a perfect example of how conflicts of interest get in the way of the truth. It doesn't matter how many people, including so-called "scientists", say the earth is flat, if a single one proves it is not flat does it? This is the truth about science that ignorant fools on government city councils or commissions are not able to comprehend, since all they can comprehend with their evidently limited or retarded brain function is mob rule. The more the federal government fails, the more they believe its foolish and false statements.

Winfield J. Abbe said...

Statement above by Professor McKinney (Fluoride 22,3, 1989) at the death of Dean Burk, Ph.D. also one of the greatest biochemists of the twentieth century in addition to Otto Warburg, M.D., Ph.D. in Germany:
IN MEMORIAM -- DEAN BURK (1904-1988), FLUORIDE, 22:3, 1989 July
by H.L. McKinney, University of Kansas; Lawrence, Kansas

Both science and the humanities have lost a major intellect with the recent death of Dean Burk, October 6, 1988, at the age of 84, Burk was born March 21, 1904, in Oakland, California, the son of Frederic Burk, who was President of what is now San Francisco State University. He entered the University of California Farm School at Davis at the age of 15 and studied agriculture. A year later, he transferred to the University of California at Berkeley, where he received his B.S. in Entomology in 1923. Four years later at the age of 23, he earned a Ph.D., in Plant Nutrition and Chemistry (1).

He continued his advanced studies as a fellow, National Research Council/International Education Board (1927-1929), successively at University College, University of London (with A.V. Hill, a Nobel laureate), the Kaiser Wilhelm Institute for Biology in Berlin, and Harvard University. In Germany he had investigated nitrogen fixation with Otto Meyerhof and also befriended Otto Warburg, both Nobel Prize winners, and their students.

He maintained a forty-year friendship with Warburg, "my greatest mentor," and perhaps the world's greatest biochemist, who worked with him in Bethesda, Maryland, on photosynthesis in 1949. From 1950 up until 1969, the year before Warburg's death, Burk spent most summers in Berlin and translated many of Warburg's "most important contributions on cancer and photosynthesis...." (2). In 1953, he became a Foreign Member of Warburg's Institute.

In 1935 Burk also had the opportunity to study in the U.S.S.R. at the Academy of Sciences (Biochemistry Institute) as a Guest Research Worker, and he returned to study in the summer of 1937 under the famous biochemists A.N. Bach and V.I. Englehardt. During the period of his government service, he spent parts of many years in England, Germany and the U.S.S.R. He also travelled throughout the world ranging from Europe to Africa and Australia, where he toured extensively in 1977. He attended countless international meetings. Linguistically, he was proficient in German and French and knew some Russian.

Burk's professional career began in 1929 as an Associate Physical Chemist, at the Fixed Nitrogen Research Laboratory, Bureau of Chemistry and Soils, Department of Agriculture in Washington, D.C. (3). In 1939 he left that job to join the National Cancer Institute (NCI) of the National Institutes of health, with which he was associated until 1974, when he reached the mandatory retirement age of 70. His government career, therefore, spanned 45 years. With the NCI, he was Senior Chemist (1939-1948), Principal Chemist (1948-1951), Head Chemist (1951-1958) and Chief Chemist (1958-1974). He was also simultaneously a faculty member, Associate Professor of Biochemistry, at the Cornell University Medical College during 1939-1941. From 1947 until his death he held the honorary post of Research Master, Graduate Faculty, George Washington University, and during 1974-1976, he was Guest Scientist at the U.S. Naval Research Institute.

His impressive list of memberships and honors is too numerous to cite completely here (4). A few examples of some of these are: Fellow, American Association for the Advancement of Science (and organizer of cancer research conferences, 1942-1945); American Association of Cancer Research; Foreign Scientific Member, Max Planck Institute of Biochemistry, Munich, Germany and also the Institute for Cell Physiology, Berlin; Society of Experimental Biology and Medicine; Honorary President, German Society of Medical Tumorotherapy; and the Royal Society of Medicine, London. He was a member of the prestigious Cosmos Club in Washington, D.C. and the Commonwealth Club of California.
Continued below:

Winfield J. Abbe said...

Aside from his major contribution to scientific literature of more than 250 articles, Dr. Burk was also recognized as a leading American authority on photosynthesis by receiving the American Chemical Society Hillebrand Prize in 1953 "For the experimental discovery of a photosynthetic energy cycle of high quantum efficiency, with demonstration of the applicability of the Einstein law of photochemical equivalence and studies of related biochemical energy transformations in cancer metabolism" (5). According to the American Chemical Society (which he joined in 1931), the stimulus for "Burk, and the principal reason for his receiving the award," was "his discovery with Otto Warburg of one quantum reaction in photosynthesis at 90% utilization efficiency of incident light" (6). Dr. Burk achieved singular honor for his distinguished cancer research in 1965 with the Gerhard Domagk Prize "for the development of procedures for distinguishing the differences between a normal cell and one damaged by cancer" (7) normally reserved for native-born German, Swiss or Austrian citizens (8).

Burk will probably be best remembered to biochemists as the co-author, with Hans Lineweaver, of the most frequently cited paper in biochemistry, "The Determination of Enzyme Dissociation Constants," in the Journal of the American Chemical Society, published in 1934 (9). With 20-20 vision of hindsight, we now view the lack of enthusiasm by the six referees of this classic article with amusement -- they recommended rejection of the article, but editor Arthur B. Lamb overruled them! -- because we see that "the double reciprocal plot usually provides, automatically and conveniently, a considerably improved weighting for linear graphics of most enzyme velocity data as a function of concentration" (10). The consequences, as one recent review of biochemistry stated: "One can hardly find any enzymological publication in which kinetic data are presented in a way other than the double reciprocal plot according to Lineweaver and Burk. The results here confirm the opinion of Dowd and Riggs (1965) [J.E. Dowd and D.E. Riggs, J. Biol. Chem., 240:863, 1965] that the popularity of the Lineweaver-Burk method is based upon the ability to provide what seems to be a good fit even wen the experimental data are poor...." (11). But, as Burk himself commented, "It is much more importantly used to test the general qualitative correctness of an assigned mechanism formulation before ascertaining the numerical values of the parameter constants involved" (12).

Burk himself has summarized his other major laboratory projects in an interview: "thermodynamics of nitrogen fixation, biochemistry, and cancer; photosynthesis with and without green plants; biology and biochemistry of nitrogen fixation by bacteria; ... trace mineral elements; B vitamins (co-discoverer of biotin); optical activities of various biochemical racemates; cancer metabolism in all kinds of cancers and leukemia in animals and humans' poloragraphic analysis of cancer and normal blood; antibiotics; cobalt models of hemoglobin-oxygen systems; cell-tissue cultures; mitochondrial control of metabolism; iron-binding compounds in blood; chromatographic separations; manometric techniques for measurement of gases; efficiency of photosynthesis in green plants; origin of cancer cells; conventional anticancer agents' mode of action; cytotoxic actions of human sera; insulin; correlation between cancer growth rate and magnitude of metabolism (Domagk Prize, 1965); purification of tobacco smoke; effects of amygdalin (Vitamin B-17, Laetrile) on cancer cells" (13). The period from 1975-1988 was sharply focused on fluoridation and cancer.

On November 18, 1974, after his retirement, Burk founded the Dean Burk Foundation "devoted to research on health, nutrition, and chronic and degenerative diseases including cancer." Two major reports (called "Briefs") were published. One focused on vitamin B-17 and also alluded briefly to vitamin B-15 and vitamin B-13 (14). Continued below:

Winfield J. Abbe said...

Burk carefully analyzed the federal food, Drug and Cosmetic Act (as amended August 1972), Title 21 USC, Chapter 11 (Definitions), Sec. 201 (321) (f), and demonstrated conclusively that amygdalin (vitamin B-17/Laetrile) is by definition, and long-standing scientific knowledge -- to which he had personally contributed -- "scientifically to be regarded as a food, a vitamin...." (15). Unfortunately, he caustically added, irresponsible human nature appeared certain to reject such an axiom in the same way the flat earth advocates reject the view of a round earth. What was true about vitamin B-17 was equally true of vitamin B-15 and vitamin B-13. (16)

The other major focus during his retirement years was on the link between fluoridation and cancer. As a result of Dr. Burk's expert views on conventional as well as nonconventional cancer therapies, he became a sought-after speaker before nonmainstream health groups during the late 1960s and an embarrassment to his superiors at the National Cancer Institute (NCI), who advocated only the traditional medical cancer therapies of surgery, chemotherapy, and radiation treatments. The NCI therefore attempted to muzzle Burk when he was invited to speak to many groups on nonorthodox treatments he was acquainted with that had shown promise. Clinton R. Miller, legislative advocate in Washington, D.C. for the National Health Federation (NHF), knew that Burk was being harassed by the NCI -- the notoriety of the maverick head of Cytochemistry was very well known -- and lobbied the NCI through Congress to release Burk to speak to health groups. The NCI refused to approve Burk's talks, but they did not **positively** disapprove his appearances, a distinction bureaucrats might be expected to make. On Sunday, July 16, 1969, during his weekend, for example, Burk delivered a talk on "Healthier Cigarettes and Cancer Prevention," to the International Association of Cancer Victims and Friends, Inc. in Los Angeles. The NCI frowned with disapproval; the IACVF groups clamored for more (17)!
Continued:

Winfield J. Abbe said...

In January 1975, shortly after retiring from the NCI, Burk spoke to the National Health Federation about Laetrile. At that time he first met John Yiamouyiannis, a Ph.D. in biochemistry who had joined the NHF as Science Director and who was a formidable combatant in the fight against fluoridation. Burk couldn't understand why Yiamouyiannis was "first wasting his time: pursuing such a dead-end subject (18).

Burk's familiarity with fluoride reached back to the very beginning of his career. As he observed in 1976, "I did my first experiments with fluoride in 1929, and was present in Meyerhof's laboratory in Berlin when Fritz Lipmann was doing his fluoride experiments in 1929" (19). Burk's friendly, but sharp, advice to Yiamouyiannis therefore had deep roots, although Yiamouyiannis doggedly continued to pursue the topic.

In about May 1975, Yiamouyiannis finished an expanded version of his fluoridation efforts comparing cancer mortality rates in some major fluoridated cities without fluoridation. The paper was sent to Clinton R. Miller, who took it to the National Cancer Institute; the reception was negative, and Miller then asked Dean Burk, whom he knew from Burk's Laetrile talks to read the paper,. Burk, again, was typically caustic, and repeated his carefully considered opinion that Yiamouyiannis was wasting his time on a "worthless" enterprise -- if there were a connection it would have been found already. Nevertheless, he agreed as a favor to Miller to read the paper and criticize it. After spending "all night" and several more days minutely analyzing the data, Burk conceded the arguments were sound, convincing, in fact, despite his strong preconceptions, probably correct (20). He then began to view the fluoridation/cancer link in an entirely new light. Miller took Yiamouyiannis to Burk's house, and an important, lengthy collaboration began.

Burk's preliminary statement on the subject was a publication of his Foundation ("Brief" No. 2) discussing the probable link between fluoridation and cancer and the Delany Amendment to federal law, which prohibits the addition of *any* carcinogen to food or water (21). If the fluoridation/cancer link is correct, then by law fluoridation must be discontinued immediately. The NCI, however, repeatedly disclaimed any connection.

Burk's preliminary statement was followed by a detailed collaborative effort between himself and Yiamouyiannis -- Burk's "second most important paper" (22). The authors showed that crude cancer death rates in the 10 largest fluoridated cities in the U.S.A. "were higher and had risen faster than those in the 10 largest nonfluoridated U.S. cities that had essentially the same crude cancer rates during the decade before fluoridation." They found that his increase occurred in persons 45-65 and 65 and over and that corrections for age, race, and sex did not eliminate the difference as suggested by the NCI (23). The bottom line was a 5-15% higher death rate (unweighted) in the fluoridated over the unfluoridated communities compared in the study (24).
Continued:

Winfield J. Abbe said...

Criticism from fluoridation proponents was swift and hostile: the authors had failed to correct for age, sex, race, and cancer site distribution, it was claimed. When proper "adjustments" (i.e., manipulations) were made -- a constant proponent theme -- all was well with fluoridation (25). Another author emphasized that population gains (demography) explained the apparent problems away (26). The battle still continues with great vehemence a decade later.

Burk's final statement on the subject, and indeed his last scientific paper, reiterates his strong scientific conviction that demographic changes of the two groups of central cities do *not* explain away the apparent causal relationship between fluoride and cancer death rate. "It is concluded that artificial fluoridation appears to cause or induce about 20-30 excess cancer deaths for every 100,000 persons exposed per year after about 15-20 years." Burk and his co-authors therefore pleaded: "In light of this conclusion, we urge the governments of civilized countries of the world to bring about a prompt end to artificial fluoridation of public water supplies" (27). Tens of thousands of unnecessary deaths -- at one time he estimated about 40,000 in the U.S.A. alone -- would thereby be averted (28). Saving lives was a primary concern of Burk, and he thought his work on fluoridation was the most important he had done during his life (29). There is no doubt that one of his most personally fulfilling moments was experienced when he received the news that he was largely responsible for the termination of fluoridation in the Netherlands (3), despite erroneous claims to the contrary (31), and his impact in Australia was widely reported in the press there (32).

Dr. Dean Burk musician, artist, scientist, sage -- lived a rich and valuable life. he published more than 250 scientific articles. He probed abstruse mysteries; he proposed profound answers. he devoted his life to science and mankind. he made an indelible mark where he has passed. The world is infinitely richer having known such a gentle, brave man of genius, industry, and altruism.

[References can be scanned and are available on request]
The above sequence of posts are from the article in Fluoride 22,3,1989 by H.L. McKinney.